5-Amino-1MQ

5-Amino-1MQ: A small-molecule NNMT inhibitor. It is not a peptide.

What is it?

A small-molecule NNMT inhibitor. It is not a peptide.

How it is studied

Nicotinamide N-methyltransferase participates in nicotinamide metabolism. Inhibiting this enzyme is investigated in cellular energy and adipose-tissue research.

What the evidence says

The reference literature is primarily based on cell and animal experiments. These models test mechanisms without establishing a human weight-loss effect.

What remains uncertain

Human efficacy, long-term exposure, and safety are not well characterized. An effect on a metabolic enzyme is not evidence of a finished therapy.

Sources & scope

NNMT inhibition in high-fat-diet mice (2017)

For in-vitro laboratory research only. Not for human or veterinary use.