AOD-9604

AOD-9604: A modified growth-hormone fragment investigated in lipid metabolism.

What is it?

A modified growth-hormone fragment investigated in lipid metabolism.

How it is studied

Its design is based on a region near the end of the growth-hormone molecule. Research examines whether that region influences fat metabolism independently of the full hormone.

What the evidence says

An early signal did not translate into benefit in a larger placebo-controlled obesity study, which did not separate from placebo on its primary endpoint.

What remains uncertain

A plausible mechanism does not outweigh a negative controlled trial. Published work does not justify promising weight loss from this reagent.

Sources & scope

FDA Pharmacy Compounding Advisory Committee briefing (2024)

For in-vitro laboratory research only. Not for human or veterinary use.